The average bus between Southampton and Houghton Regis takes 5h 19m and the fastest bus takes 3h 30m. The bus service runs several times per day from Southampton to Houghton Regis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Southampton and Houghton Regis. The earliest departure is at 4:15 AM at night, and the last departure from Southampton is at 8:30 PM which arrives into Houghton Regis at 6:45 AM. All services require a transfer at Heathrow Central Bus Station and take an average of 5h 19m. The schedules shown below are for the next available departures.


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Want to know about travelling from Southampton to Houghton Regis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Southampton to Houghton Regis. However, there are services departing from Southampton station and arriving at Houghton Regis station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 5h 19m.
Southampton to Houghton Regis bus services, operated by National Express, depart from Coach Station.
Southampton to Houghton Regis bus services, operated by National Express, arrive at Luton Station Interchange.
The distance between Southampton and Houghton Regis is 127.1 km. The road distance is 181 km.
You can take a bus from Coach Station to All Saints Church via Heathrow Central Bus Station and Luton Station Interchange in around 4h 13m.