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Southampton to Isleworth buses

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Trip Overview

The average bus between Southampton and Isleworth takes 2h 29m and the fastest bus takes 1h 58m. The bus service runs several times per day from Southampton to Isleworth. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 29m
Duration
74 mi
Distance
£14
Average price
Twice daily
Frequency

Southampton to Isleworth bus times

Buses run twice daily between Southampton and Isleworth. The earliest departure is at 2:20 AM at night, and the last departure from Southampton is at 9:25 PM which arrives into Isleworth at 12:18 AM. All services require a transfer, and take on average 2h 29m. The schedules shown below are for the next available departures.

Departing Wednesday, October 21, 2026

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    Arrives next day

    National ExpressMetroline Travel2h 53m • 1 change

Departing Thursday, October 22, 2026

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    National ExpressMetroline Travel2h 4m • 1 change
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    Arrives next day

    National ExpressMetroline Travel2h 53m • 1 change

Departing Friday, October 23, 2026

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    National ExpressMetroline Travel1h 58m • 1 change
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    Arrives next day

    National ExpressMetroline Travel2h 55m • 1 change

Departing Saturday, October 24, 2026

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    National ExpressMetroline Travel1h 58m • 1 change
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    Arrives next day

    National ExpressMetroline Travel2h 55m • 1 change

Departing Sunday, October 25, 2026

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    National ExpressMetroline Travel2h 4m • 1 change
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    Arrives next day

    National ExpressMetroline Travel2h 53m • 1 change

Departing Monday, October 26, 2026

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    National ExpressMetroline Travel2h 4m • 1 change
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    Arrives next day

    National ExpressMetroline Travel2h 53m • 1 change

Departing Tuesday, October 27, 2026

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    National ExpressMetroline Travel2h 4m • 1 change
  •  → 

    Arrives next day

    National ExpressMetroline Travel2h 53m • 1 change

Frequently asked questions

Want to know about travelling from Southampton to Isleworth? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Southampton to Isleworth.ExpandLaunch map view
  • Distance: 73.6 mi
  • Duration: 2h 29m

What companies run services between Southampton, England and Isleworth, England?

You can take a bus from Coach Station to West Thames College via Heathrow Terminal 5 in around 2h 34m.

Operators