The average bus between Southampton and Slough Station takes 2h 24m and the fastest bus takes 1h 58m. The bus service runs several times per day from Southampton to Slough Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Southampton and Slough Station. The earliest departure is at 4:05 AM at night, and the last departure from Southampton is at 4:45 PM which arrives into Slough Station at 7:20 PM. All services require a transfer at London Heathrow Airport Terminal 5 and take an average of 2h 24m. The schedules shown below are for the next available departures.

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2h 19m • 1 change
1h 58m • 1 change
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2h 43m • 1 changeWant to know about travelling from Southampton to Slough Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Southampton to Slough Station. However, there are services departing from Southampton Central Station and arriving at Wellington Street Stop D station via London Heathrow Airport Terminal 5 station. The journey, including transfers, takes approximately 2h 24m.
Southampton to Slough Station bus services, operated by FlixBus, depart from Southampton Central Station.
Southampton to Slough Station bus services, operated by Thames Valley Buses, arrive at Wellington Street Stop D station.
Book your Southampton to Slough Station bus tickets online with Omio.
The distance between Southampton and Slough Station is 88.1 km. The road distance is 102 km.
You can take a bus from Southampton Central Station to Wellington Street Stop D via London Heathrow Airport Terminal 5 and Heathrow Terminal 5 in around 2h 5m.