The average bus between Southampton and Thame takes 3h 41m and the fastest bus takes 3h 7m. The bus service runs several times per day from Southampton to Thame. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Southampton and Thame. The earliest departure is at 4:05 AM at night, and the last departure from Southampton is at 6:30 PM which arrives into Thame at 10:02 PM. All services require a transfer at Heathrow Terminal 5 and take an average of 3h 41m. The schedules shown below are for the next available departures.


3h 53m • 2 changes

4h 17m • 2 changes

3h 52m • 2 changes

3h 7m • 2 changes

3h 53m • 2 changes

4h 17m • 2 changes

3h 52m • 2 changes

3h 7m • 2 changes

3h 53m • 2 changes

4h 36m • 2 changes

3h 27m • 2 changes

3h 22m • 2 changes

3h 7m • 2 changes

3h 7m • 2 changes

3h 37m • 2 changes

3h 7m • 2 changes

4h 16m • 2 changes

3h 56m • 2 changes

4h 26m • 2 changes

3h 26m • 2 changes

4h 3m • 2 changes

4h 6m • 2 changes

3h 52m • 2 changes

3h 7m • 2 changesWant to know about travelling from Southampton to Thame? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Southampton to Thame. However, there are services departing from Southampton station and arriving at Thame station via Heathrow Terminal 5. The journey, including transfers, takes approximately 3h 41m.
Southampton to Thame bus services, operated by National Express, depart from Coach Station.
Southampton to Thame bus services, operated by National Express, arrive at Lewknor Turn M40 J6 station.
The distance between Southampton and Thame is 98.4 km. The road distance is 167 km.
You can take a bus from Coach Station to Town Hall via Heathrow Terminal 5 and Lewknor Turn M40 J6 in around 3h 19m.