The average bus between Southampton and Uxbridge takes 2h 26m and the fastest bus takes 2h 3m. There is a bus service every few hours from Southampton to Uxbridge. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Southampton and Uxbridge. The earliest departure is at 2:05 AM at night, and the last departure from Southampton is at 8:30 PM which arrives into Uxbridge at 10:58 PM. All services require a transfer, and take on average 2h 26m. The schedules shown below are for the next available departures.

2h 28m • 1 change

2h 18m • 1 change

2h 33m • 1 change

2h 37m • 1 change

2h 26m • 1 change

2h 3m • 1 change

2h 33m • 1 change

2h 33m • 1 change

2h 26m • 1 change

2h 3m • 1 change

2h 28m • 1 change

2h 38m • 1 change

2h 26m • 1 change

2h 3m • 1 change

2h 27m • 1 change

2h 18m • 1 change
Want to know about travelling from Southampton to Uxbridge? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Southampton to Uxbridge. However, there are services departing from Southampton station and arriving at Uxbridge station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 2h 26m.
Southampton to Uxbridge bus services, operated by National Express, depart from Coach Station.
Southampton to Uxbridge bus services, operated by National Express, arrive at Heathrow Central Bus Station.
The distance between Southampton and Uxbridge is 96.3 km. The road distance is 118 km.
National Express operates a bus from Coach Station to Heathrow Central Bus Station hourly. Tickets cost £12–30 and the journey takes 1h 50m.