The average bus between Southampton and Uxbridge takes 2h 22m and the fastest bus takes 1h 53m. There is a bus service every few hours from Southampton to Uxbridge. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Southampton and Uxbridge. The earliest departure is at 2:20 AM at night, and the last departure from Southampton is at 9:25 PM which arrives into Uxbridge at 11:28 PM. All services require a transfer, and take on average 2h 22m. The schedules shown below are for the next available departures.

2h 18m • 1 change
2h 38m • 1 change
2h 43m • 1 change
2h 27m • 1 change
1h 53m • 1 change
2h 13m • 1 change
2h 33m • 1 change
2h 33m • 1 change
1h 53m • 1 change
2h 13m • 1 change
2h 33m • 1 change
2h 33m • 1 change
1h 53m • 1 change
2h 13m • 1 change
2h 33m • 1 change
2h 33m • 1 change
1h 53m • 1 change
2h 13m • 1 change
2h 38m • 1 change
2h 23m • 1 changeWant to know about travelling from Southampton to Uxbridge? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Southampton to Uxbridge. However, there are services departing from Southampton station and arriving at Uxbridge station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 2h 22m.
Southampton to Uxbridge bus services, operated by National Express, depart from Coach Station.
Southampton to Uxbridge bus services, operated by National Express, arrive at Heathrow Central Bus Station.
The distance between Southampton and Uxbridge is 96.3 km. The road distance is 119 km.
National Express operates a bus from Coach Station to Heathrow Central Bus Station hourly. Tickets cost £13–35 and the journey takes 1h 55m.