Rome2Rio

Speyer to Prague buses

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Trip Overview

The average bus between Speyer and Prague takes 11h 50m and the fastest bus takes 11h 33m. There is at least one bus per day from Speyer to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 50m
Duration
548 km
Distance
Once daily
Frequency

Speyer to Prague bus times

Buses run once daily between Speyer and Prague. The earliest departure is at 9:12 PM at night, and the last departure from Speyer is at 10:12 PM which arrives into Prague at 9:45 AM. All services require a transfer at Heidelberg, Hauptbahnhof and take an average of 11h 50m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    Busverkehr Rhein-Neckar GmbHBlaBlaCar Bus11h 33m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    Busverkehr Rhein-Neckar GmbHBlaBlaCar Bus11h 33m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Busverkehr Rhein-Neckar GmbHBlaBlaCar Bus11h 33m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Busverkehr Rhein-Neckar GmbHBlaBlaCar Bus11h 33m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Busverkehr Rhein-Neckar GmbHBlaBlaCar Bus11h 33m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    Busverkehr Rhein-Neckar GmbHBlaBlaCar Bus12h 33m • 1 change

Frequently asked questions

Want to know about travelling from Speyer to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Speyer to Prague.ExpandLaunch map view
  • Distance: 548.4 km
  • Duration: 11h 50m

What companies run services between Speyer, Germany and Prague, Czechia?

You can take a bus from Speyer, Domplatz to Prague - Florenc Main Bus Terminal via Heidelberg, Hauptbahnhof and Heidelberg in around 9h 41m.

Operators