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Springfield to Myrtle Beach buses

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Trip Overview

The average bus between Springfield and Myrtle Beach takes 35h 35m and the fastest bus takes 35h 25m. The bus runs, on average, 6 times per week from Springfield to Myrtle Beach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

35h 35m
Duration
1,144 mi
Distance
$250
Average price
6 times a week
Frequency

Springfield to Myrtle Beach bus times

Buses run 6 times a week between Springfield and Myrtle Beach. The service departs Springfield at 3:25 AM at night, which arrives into Myrtle Beach at 15:50:00. All services require a transfer at St Louis Bus Station and take an average of 35h 35m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA35h 25m • 2 changes

Departing Wednesday, November 4, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA35h 25m • 2 changes

Departing Thursday, November 5, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA35h 25m • 2 changes

Departing Friday, November 6, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA35h 25m • 2 changes

Departing Saturday, November 7, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA35h 25m • 2 changes

Frequently asked questions

Want to know about travelling from Springfield to Myrtle Beach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Springfield to Myrtle Beach.ExpandLaunch map view
  • Distance: 1,143.8 mi
  • Duration: 35h 35m

What companies run services between Springfield, MO, USA and Myrtle Beach, SC, USA?

You can take a bus from Springfield CU Transit Center to Myrtle Beach Bus Station via St Louis Bus Station and Atlanta Bus Station in around 25h.

Operators