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St. Louis Airport (STL) to Key West buses

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Trip Overview

The bus between St. Louis Airport (STL) and Key West takes 2d 13h. The bus runs, on average, 5 times per week from St. Louis Airport (STL) to Key West. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 13h
Duration
1,422 mi
Distance
$305
Average price
5 times a week
Frequency

St. Louis Airport (STL) to Key West bus times

Buses run 5 times a week between St. Louis Airport (STL) and Key West. The service departs St. Louis Airport (STL) at 10:20 PM at night, which arrives into Key West at 13:02:00. All services require a transfer at St Louis Bus Station and take an average of 2d 13h. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

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    Arrives +3 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 13h • 4 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 13h • 4 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 13h • 4 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAGreyhound USAGreyhound USAKey West Transit2d 13h • 4 changes

Frequently asked questions

Want to know about travelling from St. Louis Airport (STL) to Key West? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis Airport (STL) to Key West.ExpandLaunch map view
  • Distance: 1,421.8 mi
  • Duration: 2d 13h

What companies run services between St. Louis Airport (STL), USA and Key West, FL, USA?

You can take a bus from Saint Louis to N Roosevelt & 3rd Street via St Louis Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 34h 31m.

Operators