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St. Louis to Carlisle buses

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Trip Overview

The average bus between St. Louis and Carlisle takes 23h 45m and the fastest bus takes 21h 40m. The bus service runs several times per day from St. Louis to Carlisle. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

23h 45m
Duration
826 mi
Distance
$146
Average price
Twice daily
Frequency

Bus (Greyhound)

best
  1. Take the bus from St Louis Bus Station to Harrisburg Bus Stationbus bus Greyhound US0421
21h 11m
$123–233

St. Louis to Carlisle bus times

Buses run twice daily between St. Louis and Carlisle. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:05 PM which arrives into Carlisle at 12:45 PM. All services require a transfer at Harrisburg Bus Station and take an average of 23h 45m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from St. Louis to Carlisle? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Carlisle.ExpandLaunch map view
  • Distance: 825.5 mi
  • Duration: 23h 45m

What companies run services between St. Louis, MO, USA and Carlisle, PA, USA?

Greyhound USA operates a bus from St Louis Bus Station to Harrisburg Bus Station 3 times a day. Tickets cost $120–240 and the journey takes 19h 20m.

Operators