The average bus between St. Louis and Charlotte takes 16h 53m and the fastest bus takes 16h 5m. The bus service runs several times per day from St. Louis to Charlotte. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between St. Louis and Charlotte. The earliest departure is at 9:00 AM in the morning, and the last departure from St. Louis is at 11:45 PM which arrives into Charlotte at 6:20 PM. All services require a transfer at Carbondale Intermodal Station and take an average of 16h 53m. The schedules shown below are for the next available departures.
Arrives next day

17h 5m • 1 change
Arrives next day

18h 35m • 1 change
Arrives next day

17h 5m • 1 change
Arrives next day

18h 35m • 1 change
Arrives next day

17h 5m • 1 change
Arrives next day

18h 35m • 1 change
Arrives next day

17h 5m • 1 change
Arrives next day

18h 35m • 1 change
Want to know about travelling from St. Louis to Charlotte? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Charlotte. However, there are services departing from St. Louis station and arriving at Charlotte station via Carbondale. The journey, including transfers, takes approximately 16h 53m.
St. Louis to Charlotte bus services, operated by Greyhound USA, depart from St. Louis station.
St. Louis to Charlotte bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Book your St. Louis to Charlotte bus tickets online with Greyhound USA and Flixbus USA.
The distance between St. Louis and Charlotte is 912.9 km. The road distance is 1,271 km.
You can take a bus from St. Louis to Charlotte Bus Station via Carbondale Intermodal Station, Atlanta Bus Station, Garnett Station, Civic Center Station, and Atlanta Downtown in around 16h 24m.