- Distance: 316.5 mi
- Duration: 6h 8m
The average bus between St. Louis and Chicago Bus Station takes 6h 8m and the fastest bus takes 6h 5m. The bus service runs several times per day from St. Louis to Chicago Bus Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between St. Louis and Chicago Bus Station. The earliest departure is at 10:00 AM in the morning, and the last departure from St. Louis is at 11:30 PM which arrives into Chicago Bus Station at 5:45 AM. All services run direct with no transfers required, and take on average 6h 8m. The schedules shown below are for the next available departures.
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Arrives next day
Arrives next day
Arrives next day
Want to know about travelling from St. Louis to Chicago Bus Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from St. Louis station and arriving at Chicago Bus Station station. Services depart 3 times a day, and operate Once daily. The journey takes approximately 6h 8m.
St. Louis to Chicago Bus Station bus services, operated by Flixbus USA, depart from St Louis Bus Station.
St. Louis to Chicago Bus Station bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Book your St. Louis to Chicago Bus Station bus tickets online with Flixbus USA.
The distance between St. Louis and Chicago Bus Station is 421.1 km. The road distance is 509 km.
Flixbus USA operates a bus from St Louis Bus Station to Chicago Bus Station twice daily. Tickets cost $50–85 and the journey takes 6h 5m.
