- Distance: 242 mi
- Duration: 4h 33m
The average bus between St. Louis and Downtown Indianapolis takes 4h 33m and the fastest bus takes 4h 25m. The bus service runs several times per day from St. Louis to Downtown Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between St. Louis and Downtown Indianapolis. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:05 PM which arrives into Downtown Indianapolis at 7:30 PM. All services run direct with no transfers required, and take on average 4h 33m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Downtown Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from St. Louis station and arriving at Downtown Indianapolis station. Services depart 3 times a day, and operate Twice daily. The journey takes approximately 4h 33m.
St. Louis to Downtown Indianapolis bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Downtown Indianapolis bus services, operated by Greyhound USA, arrive at Indianapolis Union Station.
Book your St. Louis to Downtown Indianapolis bus tickets online with Greyhound USA.
The distance between St. Louis and Downtown Indianapolis is 370.4 km. The road distance is 390 km.
Greyhound-us operates a bus from St Louis Bus Station to Indianapolis Union Station 3 times a day, and the journey takes 4h 25m. Greyhound USA also services this route 3 times a day.
