The bus between St. Louis and Florence takes 36h 45m. The bus runs, on average, 5 times per week from St. Louis to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between St. Louis and Florence. The earliest departure is at 11:45 PM at night, and the last departure from St. Louis is at 11:45 PM which arrives into Florence at 1:30 PM. All services require a transfer at Carbondale Intermodal Station and take an average of 36h 45m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Florence. However, there are services departing from St. Louis station and arriving at Florence station via Carbondale. The journey, including transfers, takes approximately 36h 45m.
St. Louis to Florence bus services, operated by Flixbus USA, depart from St. Louis station.
St. Louis to Florence bus services, operated by Flixbus USA, arrive at Florence Bus Station.
Book your St. Louis to Florence bus tickets online with Flixbus USA and Greyhound USA.
The distance between St. Louis and Florence is 1,054.9 km. The road distance is 1,363 km.
You can take a bus from St. Louis to Florence Bus Station via Carbondale Intermodal Station and Atlanta Bus Station in around 18h 25m.
