The average bus between St. Louis and Jacksonville takes 21h 6m and the fastest bus takes 20h 15m. The bus service runs several times per day from St. Louis to Jacksonville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between St. Louis and Jacksonville. The earliest departure is at 9:00 AM in the morning, and the last departure from St. Louis is at 11:40 PM which arrives into Jacksonville at 10:10 PM. All services require a transfer, and take on average 21h 6m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Jacksonville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Jacksonville. However, there are services departing from St Louis Bus Station and arriving at Jacksonville station via Atlanta Bus Station. The journey, including transfers, takes approximately 21h 6m.
St. Louis to Jacksonville bus services, operated by Flixbus USA, depart from St Louis Bus Station.
St. Louis to Jacksonville bus services, operated by Flixbus USA, arrive at Jacksonville station.
Book your St. Louis to Jacksonville bus tickets online with Omio and FlixBus.
The distance between St. Louis and Jacksonville is 1208.7 km. The road distance is 1383 km.
You can take a bus from St Louis Bus Station to Jacksonville via Atlanta Bus Station in around 17h 45m.
