The average bus between St. Louis and Lafayette takes 12h 22m and the fastest bus takes 9h 15m. The bus service runs several times per day from St. Louis to Lafayette. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between St. Louis and Lafayette. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:05 PM which arrives into Lafayette at 6:35 AM. All services require a transfer, and take on average 12h 22m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Lafayette? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Lafayette. However, there are services departing from St. Louis station and arriving at Lafayette station via Indianapolis Union Station station. The journey, including transfers, takes approximately 12h 22m.
St. Louis to Lafayette bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Lafayette bus services, operated by Greyhound USA, arrive at Lafayette Amtrak Station.
Book your St. Louis to Lafayette bus tickets online with Greyhound USA and Amtrak Thruway.
The distance between St. Louis and Lafayette is 347.5 km. The road distance is 493 km.
You can take a bus from St Louis Bus Station to Lafayette Amtrak Station via Indianapolis Union Station in around 6h 45m.
