The bus between St. Louis and Louisville takes 23h. The bus runs, on average, 6 times per week from St. Louis to Louisville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between St. Louis and Louisville. The earliest departure is at 1:45 PM in the afternoon, and the last departure from St. Louis is at 1:45 PM which arrives into Louisville at 1:45 PM. All services require a transfer, and take on average 23h. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Louisville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Louisville. However, there are services departing from St. Louis station and arriving at Louisville station via Evansville Bus Station station. The journey, including transfers, takes approximately 23h.
St. Louis to Louisville bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Louisville bus services, operated by Greyhound USA, arrive at Louisville, KY station.
Book your St. Louis to Louisville bus tickets online with Greyhound USA and Miller Transportation.
The distance between St. Louis and Louisville is 388.7 km. The road distance is 457 km.
You can take a bus from St Louis Bus Station to Louisville, KY via Evansville, IN in around 6h 40m.
