The bus between St. Louis and Louisville takes 27h 17m. The bus runs, on average, 5 times per week from St. Louis to Louisville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between St. Louis and Louisville. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:00 AM which arrives into Louisville at 6:17 AM. All services require a transfer at Cambridge, OH and take an average of 27h 17m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Louisville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Louisville. However, there are services departing from St. Louis station and arriving at Louisville station via Cambridge, OH. The journey, including transfers, takes approximately 27h 17m.
St. Louis to Louisville bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Louisville bus services, operated by Greyhound USA, arrive at Canton station.
The distance between St. Louis and Louisville is 802.4 km. The road distance is 928 km.
You can take a bus from St Louis Bus Station to E Main St And N Chapel St via Cambridge, OH, Cambridge, and Cornerstone Transit Center in around 16h 8m.
