Rome2Rio

St. Louis to Manchester buses

Find Transport to Manchester

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The average bus between St. Louis and Manchester takes 35h 45m and the fastest bus takes 35h 40m. The bus service runs several times per day from St. Louis to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

35h 45m
Duration
1,285 mi
Distance
$291
Average price
Twice daily
Frequency

St. Louis to Manchester bus times

Buses run twice daily between St. Louis and Manchester. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 8:45 AM which arrives into Manchester at 9:35 PM. All services require a transfer at Port Authority Bus Terminal and take an average of 35h 45m. The schedules shown below are for the next available departures.

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Greyhound USATrailwaysVermont Translines35h 40m • 2 changes
  •  → 

    Arrives next day

    Greyhound USATrailwaysVermont Translines35h 50m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Greyhound USATrailwaysVermont Translines35h 40m • 2 changes
  •  → 

    Arrives next day

    Greyhound USATrailwaysVermont Translines35h 50m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Greyhound USATrailwaysVermont Translines35h 40m • 2 changes
  •  → 

    Arrives next day

    Greyhound USATrailwaysVermont Translines35h 50m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Greyhound USATrailwaysVermont Translines35h 40m • 2 changes
  •  → 

    Arrives next day

    Greyhound USATrailwaysVermont Translines35h 50m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    Greyhound USATrailwaysVermont Translines35h 40m • 2 changes
  •  → 

    Arrives next day

    Greyhound USATrailwaysVermont Translines35h 50m • 2 changes

Frequently asked questions

Want to know about travelling from St. Louis to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Manchester.ExpandLaunch map view
  • Distance: 1,285.2 mi
  • Duration: 35h 45m

What companies run services between St. Louis, MO, USA and Manchester, VT, USA?

You can take a bus from St Louis Bus Station to Bus Parking Area Manchester via Port Authority Bus Terminal, New York, Albany, and Greyhound \ Trailways Terminal in around 30h 57m.

Operators