Rome2Rio

St. Louis to Mechanicsburg buses

Find Transport to Mechanicsburg

View schedule

Trip Overview

The average bus between St. Louis and Mechanicsburg takes 22h 41m and the fastest bus takes 20h 41m. The bus service runs several times per day from St. Louis to Mechanicsburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 41m
Duration
814 mi
Distance
$215
Average price
Twice daily
Frequency

Bus

best
  1. Take the bus from St Louis Bus Station to Harrisburg Bus Stationbus bus Greyhound US0421
20h 24m
$179–246

St. Louis to Mechanicsburg bus times

Buses run twice daily between St. Louis and Mechanicsburg. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:05 PM which arrives into Mechanicsburg at 11:58 AM. All services require a transfer at Harrisburg Bus Station and take an average of 22h 41m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from St. Louis to Mechanicsburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Mechanicsburg.ExpandLaunch map view
  • Distance: 813.9 mi
  • Duration: 22h 41m

What companies run services between St. Louis, MO, USA and Mechanicsburg, Cumberland County, PA, USA?

Greyhound USA operates a bus from St Louis Bus Station to Harrisburg Bus Station 3 times a day. Tickets cost $130–250 and the journey takes 19h 20m. Jefferson Lines also services this route 3 times a day.

Operators