Rome2Rio

St. Louis to Meridian buses

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Trip Overview

The average bus between St. Louis and Meridian takes 12h 55m and the fastest bus takes 9h 55m. The bus runs, on average, 5 times per week from St. Louis to Meridian. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 55m
Duration
527 mi
Distance
$107
Average price
5 times a week
Frequency

St. Louis to Meridian bus times

Buses run 5 times a week between St. Louis and Meridian. The earliest departure is at 1:00 AM at night, and the last departure from St. Louis is at 4:00 PM which arrives into Meridian at 1:55 AM. All services require a transfer, and take on average 12h 55m. The schedules shown below are for the next available departures.

Departing Friday, November 13, 2026

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    Arrives next day

    Flixbus USAFlixbus USA9h 55m • 1 change

Departing Saturday, November 14, 2026

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    Arrives next day

    Flixbus USAFlixbus USA9h 55m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA9h 55m • 1 change

Departing Monday, November 16, 2026

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    Arrives next day

    Flixbus USAFlixbus USA9h 55m • 1 change

Departing Tuesday, November 17, 2026

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    Arrives next day

    Greyhound USAFlixbus USA24h 55m • 1 change

Frequently asked questions

Want to know about travelling from St. Louis to Meridian? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Meridian.ExpandLaunch map view
  • Distance: 526.6 mi
  • Duration: 12h 55m

What companies run services between St. Louis, MO, USA and Meridian, MS, USA?

You can take a bus from St Louis Bus Station to Meridian Bus Stop via Memphis Bus Station in around 10h 50m.

Operators