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St. Louis to Midlothian buses

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Trip Overview

The average bus between St. Louis and Midlothian takes 11h 46m and the fastest bus takes 7h 2m. The bus runs, on average, 5 times per week from St. Louis to Midlothian. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 46m
Duration
327 mi
Distance
$58
Average price
5 times a week
Frequency

St. Louis to Midlothian bus times

Buses run 5 times a week between St. Louis and Midlothian. The earliest departure is at 11:30 PM at night, and the last departure from St. Louis is at 11:30 PM which arrives into Midlothian at 6:32 AM. All services require a transfer at Chicago and take an average of 11h 46m. The schedules shown below are for the next available departures.

Departing Thursday, October 15, 2026

  •  → 

    Arrives next day

    Flixbus USAPace BusPace Bus7h 2m • 2 changes

Departing Friday, October 16, 2026

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    Arrives next day

    Flixbus USAPace BusPace Bus7h 2m • 2 changes

Departing Saturday, October 17, 2026

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    Arrives +2 days

    Flixbus USAPace BusPace Bus30h 44m • 2 changes

Departing Sunday, October 18, 2026

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    Arrives next day

    Flixbus USAPace BusPace Bus7h 2m • 2 changes

Departing Monday, October 19, 2026

  •  → 

    Arrives next day

    Flixbus USAPace BusPace Bus7h 2m • 2 changes

Frequently asked questions

Want to know about travelling from St. Louis to Midlothian? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Midlothian.ExpandLaunch map view
  • Distance: 327.4 mi
  • Duration: 11h 46m

What companies run services between St. Louis, MO, USA and Midlothian, IL, USA?

Flixbus USA operates a bus from St Louis Bus Station to Chicago 5 times a week. Tickets cost $45–70 and the journey takes 5h 40m.

Operators