The average bus between St. Louis and Niles takes 7h 30m and the fastest bus takes 7h 11m. The bus service runs several times per day from St. Louis to Niles. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between St. Louis and Niles. The earliest departure is at 10:00 AM in the morning, and the last departure from St. Louis is at 11:30 PM which arrives into Niles at 6:57 AM. All services require a transfer at Chicago Bus Station and take an average of 7h 30m. The schedules shown below are for the next available departures.


7h 42m • 2 changes


7h 31m • 2 changes
Arrives next day


7h 13m • 2 changes


7h 29m • 2 changes


7h 32m • 2 changes
Arrives next day


7h 11m • 2 changes


7h 28m • 2 changes


7h 31m • 2 changes
Arrives next day


7h 27m • 2 changes


7h 42m • 2 changes


7h 31m • 2 changes
Arrives next day


7h 27m • 2 changes
Want to know about travelling from St. Louis to Niles? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Niles. However, there are services departing from St. Louis station and arriving at Niles station via Chicago Bus Station station. The journey, including transfers, takes approximately 7h 30m.
St. Louis to Niles bus services, operated by Flixbus USA, depart from St Louis Bus Station.
St. Louis to Niles bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
The distance between St. Louis and Niles is 428.3 km. The road distance is 534 km.
FlixBus-us operates a bus from St Louis Bus Station to Chicago Bus Station 3 times a day, and the journey takes 6h 5m. Flixbus USA also services this route twice daily.