The average bus between St. Louis and North Carolina takes 16h 53m and the fastest bus takes 16h 5m. The bus service runs several times per day from St. Louis to North Carolina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between St. Louis and North Carolina. The earliest departure is at 9:00 AM in the morning, and the last departure from St. Louis is at 11:45 PM which arrives into North Carolina at 6:20 PM. All services require a transfer, and take on average 16h 53m. The schedules shown below are for the next available departures.
Arrives next day

17h 5m • 1 change
Arrives next day

18h 35m • 1 change
Arrives next day

17h 5m • 1 change
Arrives next day

18h 35m • 1 change
Arrives next day

17h 5m • 1 change
Arrives next day

18h 35m • 1 change
Arrives next day

17h 5m • 1 change
Arrives next day

18h 35m • 1 change
Want to know about travelling from St. Louis to North Carolina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to North Carolina. However, there are services departing from St. Louis station and arriving at North Carolina station via Atlanta Bus Station station. The journey, including transfers, takes approximately 16h 53m.
St. Louis to North Carolina bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to North Carolina bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Book your St. Louis to North Carolina bus tickets online with Greyhound USA and Flixbus USA.
The distance between St. Louis and North Carolina is 1,041.3 km. The road distance is 1,270 km.
You can take a bus from St Louis Bus Station to Charlotte Bus Station via Atlanta Bus Station in around 15h 30m.