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St. Louis to North Carolina buses

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Trip Overview

The average bus between St. Louis and North Carolina takes 17h 1m and the fastest bus takes 16h 5m. The bus service runs several times per day from St. Louis to North Carolina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 1m
Duration
804 mi
Distance
$169
Average price
Twice daily
Frequency

St. Louis to North Carolina bus times

Buses run twice daily between St. Louis and North Carolina. The earliest departure is at 9:00 AM in the morning, and the last departure from St. Louis is at 11:40 PM which arrives into North Carolina at 6:20 PM. All services require a transfer at Atlanta Bus Station and take an average of 17h 1m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    Greyhound USAGreyhound USA16h 5m • 1 change
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    Arrives next day

    Flixbus USAFlixbus USA17h 40m • 1 change

Departing Monday, November 9, 2026

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    Arrives next day

    Greyhound USAGreyhound USA16h 5m • 1 change
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    Arrives next day

    Flixbus USAGreyhound USA20h 5m • 1 change

Departing Tuesday, November 10, 2026

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    Arrives next day

    Greyhound USAGreyhound USA16h 5m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAGreyhound USA16h 5m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USA16h 5m • 1 change
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    Arrives next day

    Flixbus USAFlixbus USA17h 40m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USA16h 5m • 1 change
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    Arrives next day

    Flixbus USAFlixbus USA17h 40m • 1 change

Frequently asked questions

Want to know about travelling from St. Louis to North Carolina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to North Carolina.ExpandLaunch map view
  • Distance: 804.4 mi
  • Duration: 17h 1m

What companies run services between St. Louis, MO, USA and North Carolina, USA?

You can take a bus from St Louis Bus Station to Charlotte Bus Station via Atlanta Bus Station, Garnett Station, Civic Center Station, and Atlanta Downtown in around 16h 59m.

Operators