The average bus between St. Louis and Plymouth takes 33h 20m and the fastest bus takes 31h 35m. The bus service runs several times per day from St. Louis to Plymouth. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between St. Louis and Plymouth. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:05 PM which arrives into Plymouth at 12:40 AM. All services require a transfer at Port Authority Bus Terminal and take an average of 33h 20m. The schedules shown below are for the next available departures.
Arrives next day


35h 20m • 2 changes
Arrives next day


32h 35m • 2 changes
Arrives +2 days


34h 35m • 2 changes
Arrives next day


35h 20m • 2 changes
Arrives next day


32h 35m • 2 changes
Arrives +2 days


34h 35m • 2 changes
Arrives next day


35h 20m • 2 changes
Arrives next day


33h 35m • 2 changes
Arrives +2 days


34h 35m • 2 changes
Want to know about travelling from St. Louis to Plymouth? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Plymouth. However, there are services departing from St. Louis station and arriving at Plymouth station via Port Authority Bus Terminal. The journey, including transfers, takes approximately 33h 20m.
St. Louis to Plymouth bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Plymouth bus services, operated by Greyhound USA, arrive at Park & Ride Lot, Ex 13 Info. Ctr. station.
The distance between St. Louis and Plymouth is 1,693.4 km. The road distance is 2,099 km.
You can take a bus from St Louis Bus Station to Park & Ride Lot, Ex 13 Info. Ctr. via Port Authority Bus Terminal, New York, Boston, and Boston South Buses in around 31h 54m.