The average bus between St. Louis and Reading takes 25h 45m and the fastest bus takes 23h 50m. There is at least one bus per day from St. Louis to Reading. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between St. Louis and Reading. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:05 PM which arrives into Reading at 6:45 PM. All services require a transfer, and take on average 25h 45m. The schedules shown below are for the next available departures.
Arrives next day

23h 50m • 1 changeArrives next day

27h 40m • 1 changeArrives next day

23h 50m • 1 changeArrives next day

27h 40m • 1 changeArrives next day

23h 50m • 1 changeArrives next day

27h 40m • 1 changeWant to know about travelling from St. Louis to Reading? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Reading. However, there are services departing from St. Louis station and arriving at Reading station via Harrisburg Bus Station station. The journey, including transfers, takes approximately 25h 45m.
St. Louis to Reading bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Reading bus services, operated by Greyhound USA, arrive at Reading station.
Book your St. Louis to Reading bus tickets online with Greyhound USA and Flixbus USA.
The distance between St. Louis and Reading is 1,238 km. The road distance is 1,391 km.
You can take a bus from St Louis Bus Station to Reading via Harrisburg Bus Station in around 22h 5m.