The average bus between St. Louis and Reading takes 25h 52m and the fastest bus takes 24h 5m. The bus service runs several times per day from St. Louis to Reading. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between St. Louis and Reading. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:05 PM which arrives into Reading at 6:45 PM. All services require a transfer, and take on average 25h 52m. The schedules shown below are for the next available departures.
Arrives next day

25h 5m • 1 change
Arrives next day

28h 40m • 1 change
Arrives next day

25h 5m • 1 change
Arrives next day

28h 40m • 1 change
Arrives next day

25h 5m • 1 change
Arrives next day

28h 40m • 1 change
Want to know about travelling from St. Louis to Reading? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Reading. However, there are services departing from St. Louis station and arriving at Reading station via Harrisburg Bus Station station. The journey, including transfers, takes approximately 25h 52m.
St. Louis to Reading bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Reading bus services, operated by Greyhound USA, arrive at Reading station.
Book your St. Louis to Reading bus tickets online with Greyhound USA and Flixbus USA.
The distance between St. Louis and Reading is 1,238 km. The road distance is 1,391 km.
You can take a bus from St Louis Bus Station to Reading via Harrisburg Bus Station in around 21h 35m.