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St. Louis to Salem buses

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Trip Overview

The bus between St. Louis and Salem takes 46h 35m. The bus runs, on average, 6 times per week from St. Louis to Salem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

46h 35m
Duration
2,273 mi
Distance
$487
Average price
6 times a week
Frequency

St. Louis to Salem bus times

Buses run 6 times a week between St. Louis and Salem. The service departs St. Louis at 11:45 PM at night, which arrives into Salem at 20:20:00. All services require a transfer at Denver Union Station and take an average of 46h 35m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA46h 35m • 2 changes

Departing Sunday, November 8, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA46h 35m • 2 changes

Departing Monday, November 9, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA46h 35m • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA46h 35m • 2 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA46h 35m • 2 changes

Frequently asked questions

Want to know about travelling from St. Louis to Salem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Salem.ExpandLaunch map view
  • Distance: 2,272.8 mi
  • Duration: 46h 35m

What companies run services between St. Louis, MO, USA and Salem, OR, USA?

You can take a bus from St Louis Bus Station to Salem via Denver Union Station and Pasco Bus Stop in around 47h 50m.

Operators