The bus between St. Louis and Syracuse takes 23h 25m. There is at least one bus per day from St. Louis to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between St. Louis and Syracuse. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:00 AM which arrives into Syracuse at 2:25 AM. All services require a transfer at Columbus - Mound St and take an average of 23h 25m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Syracuse. However, there are services departing from St. Louis station and arriving at Syracuse station via Columbus. The journey, including transfers, takes approximately 23h 25m.
St. Louis to Syracuse bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Syracuse bus services, operated by Greyhound USA, arrive at Syracuse Bus Station.
Book your St. Louis to Syracuse bus tickets online with Greyhound USA, Barons Bus and 2 other operators.
The distance between St. Louis and Syracuse is 1,278.1 km. The road distance is 1,498 km.
You can take a bus from St Louis Bus Station to Syracuse Bus Station via Columbus - Mound St, Buffalo, NY, and Buffalo in around 20h 45m.
