The average bus between St. Louis and Ypsilanti takes 17h 4m and the fastest bus takes 14h 26m. The bus service runs several times per day from St. Louis to Ypsilanti. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between St. Louis and Ypsilanti. The earliest departure is at 12:30 AM at night, and the last departure from St. Louis is at 11:30 PM which arrives into Ypsilanti at 11:56 PM. All services require a transfer at Chicago Bus Station and take an average of 17h 4m. The schedules shown below are for the next available departures.
Arrives next day



17h 56m • 3 changes
Arrives next day



15h 26m • 3 changes
Arrives next day



18h 56m • 3 changes
Arrives next day



15h 26m • 3 changes
Arrives next day



17h • 3 changes
Arrives next day



15h 26m • 3 changes
Want to know about travelling from St. Louis to Ypsilanti? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Ypsilanti. However, there are services departing from St. Louis station and arriving at Ypsilanti station via Chicago Bus Station station. The journey, including transfers, takes approximately 17h 4m.
St. Louis to Ypsilanti bus services, operated by Flixbus USA, depart from St Louis Bus Station.
St. Louis to Ypsilanti bus services, operated by Flixbus USA, arrive at Ann Arbor station.
The distance between St. Louis and Ypsilanti is 686.7 km. The road distance is 926 km.
You can take a bus from St Louis Bus Station to YTC - EndPt via Chicago Bus Station, Ann Arbor, Beakes + Summit, and BTC - Fourth Ave Stop 1 in around 13h 30m.