Bus Stoke-on-Trent to Southampton from £38 | Tickets & Timetables

Stoke-on-Trent to Southampton buses

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Trip Overview

The average bus between Stoke-on-Trent and Southampton takes 6h 34m and the fastest bus takes 5h 40m. The bus service runs several times per day from Stoke-on-Trent to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 34m
Duration: 224 mi
Distance: £38
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from Stoke-on-Trent to London Heathrow Airportbus Uk980 / ...
Take the bus from Heathrow Central Bus Station to Coach Stationbus 032

5h 52m

£31–62

Stoke-on-Trent to Southampton bus times

Buses run every 4 hours between Stoke-on-Trent and Southampton. The earliest departure is at 1:45 AM at night, and the last departure from Stoke-on-Trent is at 4:50 PM which arrives into Southampton at 10:45 PM. All services require a transfer, and take on average 6h 34m. The schedules shown below are for the next available departures.

Departing Monday, August 17, 2026

3:20 PM → 9:50 PM
6h 30m • 1 change
4:50 PM → 10:45 PM
5h 55m • 1 change

Departing Tuesday, August 18, 2026

1:45 AM → 9:30 AM
7h 45m • 1 change
6:15 AM → 12:50 PM
6h 35m • 1 change
10:05 AM → 3:55 PM
5h 50m • 1 change
3:20 PM → 9:00 PM
5h 40m • 1 change
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Departing Wednesday, August 19, 2026

1:45 AM → 9:30 AM
7h 45m • 1 change
6:15 AM → 12:50 PM
6h 35m • 1 change
10:05 AM → 3:55 PM
5h 50m • 1 change
3:20 PM → 9:00 PM
5h 40m • 1 change
Show more

Departing Thursday, August 20, 2026

1:45 AM → 9:30 AM
7h 45m • 1 change
6:15 AM → 12:50 PM
6h 35m • 1 change
10:05 AM → 3:55 PM
5h 50m • 1 change
3:20 PM → 9:00 PM
5h 40m • 1 change
Show more

Departing Friday, August 21, 2026

1:45 AM → 9:30 AM
7h 45m • 1 change
6:15 AM → 12:50 PM
6h 35m • 1 change
10:05 AM → 5:05 PM
7h • 1 change
3:20 PM → 9:50 PM
6h 30m • 1 change
Show more

Departing Saturday, August 22, 2026

1:45 AM → 9:50 AM
8h 5m • 1 change
6:15 AM → 12:50 PM
6h 35m • 1 change
10:05 AM → 4:20 PM
6h 15m • 1 change
3:20 PM → 9:50 PM
6h 30m • 1 change
Show more

Departing Sunday, August 23, 2026

1:45 AM → 9:50 AM
8h 5m • 1 change
6:15 AM → 12:50 PM
6h 35m • 1 change
10:05 AM → 4:20 PM
6h 15m • 1 change
3:20 PM → 9:50 PM
6h 30m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Stoke-on-Trent to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.