The average bus between Strasbourg (Station) and Frankfurt am Main takes 4h 50m and the fastest bus takes 3h 50m. There is a bus service every few hours from Strasbourg (Station) to Frankfurt am Main. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Strasbourg (Station) and Frankfurt am Main. The earliest departure is at 12:34 AM at night, and the last departure from Strasbourg (Station) is at 11:54 PM which arrives into Frankfurt am Main at 3:50 AM. All services require a transfer at Etoile Bourse and take an average of 4h 50m. The schedules shown below are for the next available departures.


4h 11m • 2 changes


5h 51m • 2 changes
Arrives next day


4h 19m • 2 changes


2h 16m • 2 changes


5h 26m • 2 changes


3h 56m • 2 changes


4h 1m • 2 changes


4h 55m • 2 changes


5h 26m • 2 changes


3h 56m • 2 changes


4h 1m • 2 changes


4h 55m • 2 changes


5h 26m • 2 changes


3h 56m • 2 changes


4h 1m • 2 changes


4h 55m • 2 changes
Want to know about travelling from Strasbourg (Station) to Frankfurt am Main? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Strasbourg (Station) to Frankfurt am Main. However, there are services departing from Strasbourg (Station) station and arriving at Frankfurt am Main station via Karlsruhe central train station station. The journey, including transfers, takes approximately 4h 50m.
Strasbourg (Station) to Frankfurt am Main bus services, operated by CTS - Compagnie des Transports Strasbourgeois, depart from Strasbourg station.
Strasbourg (Station) to Frankfurt am Main bus services, operated by CTS - Compagnie des Transports Strasbourgeois, arrive at Frankfurt central train station.
The distance between Strasbourg (Station) and Frankfurt am Main is 183.6 km. The road distance is 247 km.
You can take a bus from Gare Centrale to Frankfurt central train station via Etoile Bourse, Strasbourg, and Karlsruhe central train station in around 4h 46m.