The average bus between Strasbourg (Station) and Lyon takes 7h 24m and the fastest bus takes 6h 35m. The bus service runs several times per day from Strasbourg (Station) to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Strasbourg (Station) and Lyon. The earliest departure is at 12:34 AM at night, and the last departure from Strasbourg (Station) is at 9:54 PM which arrives into Lyon at 5:10 AM. All services require a transfer at Etoile Bourse and take an average of 7h 24m. The schedules shown below are for the next available departures.

7h 41m • 1 change
7h 26m • 1 change
8h • 1 change
6h 45m • 1 change
7h 41m • 1 change
7h 36m • 1 change
7h 56m • 1 change
6h 35m • 1 change
7h 41m • 1 change
7h 36m • 1 change
7h 56m • 1 change
6h 35m • 1 change
7h 41m • 1 change
7h 36m • 1 change
7h 56m • 1 change
6h 35m • 1 changeWant to know about travelling from Strasbourg (Station) to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Strasbourg (Station) to Lyon. However, there are services departing from Strasbourg station and arriving at Lyon station via Lyon station. The journey, including transfers, takes approximately 7h 24m.
Strasbourg (Station) to Lyon bus services, operated by FlixBus, depart from Strasbourg station.
Strasbourg (Station) to Lyon bus services, operated by FlixBus, arrive at Lyon station.
The distance between Strasbourg (Station) and Lyon is 383.5 km. The road distance is 457 km.
FlixBus operates a bus from Strasbourg to Lyon every 4 hours. Tickets cost €40–65 and the journey takes 6h 55m. BlaBlaCar Bus also services this route 3 times a day.