The average bus between Strasbourg (Station) and Lyon takes 7h 39m and the fastest bus takes 6h 36m. The bus service runs several times per day from Strasbourg (Station) to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Strasbourg (Station) and Lyon. The earliest departure is at 12:34 AM at night, and the last departure from Strasbourg (Station) is at 9:54 PM which arrives into Lyon at 5:10 AM. All services require a transfer at Etoile Bourse and take an average of 7h 39m. The schedules shown below are for the next available departures.

6h 37m • 1 change
Arrives next day

7h 34m • 1 change
Arrives next day

8h 21m • 1 change
Arrives next day

5h 6m • 1 change

7h 41m • 1 change

7h 36m • 1 change

8h 45m • 1 change

7h 56m • 1 change

7h 41m • 1 change

7h 36m • 1 change

8h 45m • 1 change

7h 56m • 1 change

7h 41m • 1 change

7h 36m • 1 change

8h 45m • 1 change

7h 56m • 1 change

7h 41m • 1 change

7h 36m • 1 change

8h 45m • 1 change

7h 56m • 1 change

7h 41m • 1 change

7h 26m • 1 change

9h 1m • 1 change

7h 52m • 1 change
Want to know about travelling from Strasbourg (Station) to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Strasbourg (Station) to Lyon. However, there are services departing from Strasbourg (Station) station and arriving at Lyon station via Lyon. The journey, including transfers, takes approximately 7h 39m.
Strasbourg (Station) to Lyon bus services, operated by CTS - Compagnie des Transports Strasbourgeois, depart from Strasbourg station.
Strasbourg (Station) to Lyon bus services, operated by CTS - Compagnie des Transports Strasbourgeois, arrive at Lyon station.
The distance between Strasbourg (Station) and Lyon is 383.5 km. The road distance is 497 km.
FlixBus operates a bus from Strasbourg to Lyon every 4 hours. Tickets cost €40–70 and the journey takes 6h 45m. BlaBlaCar Bus also services this route 5 times a day.