Strasbourg to Main Buses

Trip Overview

The average bus between Strasbourg and Main takes 6h 16m and the fastest bus takes 5h 2m. The bus service runs several times per day from Strasbourg to Main. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 16m
Duration: 261 km
Distance: €23
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from Strasbourg to Frankfurt Airportbus FlixBus 108 / ...

5h 17m

€15–30

Strasbourg to Main bus times

Buses run every 4 hours between Strasbourg and Main. The earliest departure is at 3:30 AM at night, and the last departure from Strasbourg is at 8:35 PM which arrives into Main at 6:57 AM. All services require a transfer at Frankfurt Airport and take an average of 6h 16m. The schedules shown below are for the next available departures.

Departing Tuesday, October 13, 2026

8:35 PM → 6:57 AM
Arrives next day
10h 22m • 2 changes

Departing Wednesday, October 14, 2026

3:30 AM → 10:57 AM
5h 27m • 2 changes
8:50 AM → 2:27 PM
5h 37m • 2 changes
9:00 AM → 2:57 PM
5h 57m • 2 changes
10:25 AM → 3:27 PM
5h 2m • 2 changes
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Departing Thursday, October 15, 2026

3:30 AM → 10:57 AM
5h 27m • 2 changes
8:50 AM → 2:27 PM
5h 37m • 2 changes
9:00 AM → 2:57 PM
5h 57m • 2 changes
10:25 AM → 3:57 PM
5h 32m • 2 changes
Show more

Departing Friday, October 16, 2026

3:30 AM → 10:57 AM
5h 27m • 2 changes
8:50 AM → 2:27 PM
5h 37m • 2 changes
9:00 AM → 2:57 PM
5h 57m • 2 changes
10:25 AM → 3:57 PM
5h 32m • 2 changes
Show more

Departing Saturday, October 17, 2026

3:30 AM → 10:57 AM
5h 27m • 2 changes
8:50 AM → 2:27 PM
5h 37m • 2 changes
9:00 AM → 2:57 PM
5h 57m • 2 changes
10:25 AM → 3:57 PM
5h 32m • 2 changes
Show more

Departing Sunday, October 18, 2026

3:30 AM → 10:34 AM
5h 4m • 2 changes
9:00 AM → 2:52 PM
5h 52m • 2 changes
10:25 AM → 3:52 PM
5h 27m • 2 changes
11:30 AM → 7:52 PM
6h 22m • 2 changes
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Departing Monday, October 19, 2026

3:30 AM → 10:57 AM
5h 27m • 2 changes
8:50 AM → 2:27 PM
5h 37m • 2 changes
9:00 AM → 2:57 PM
5h 57m • 2 changes
10:25 AM → 3:57 PM
5h 32m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Strasbourg to Main? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Strasbourg, France and Main, Hesse, Germany?

FlixBus operates a bus from Strasbourg to Frankfurt Airport 5 times a day. Tickets cost €19–30 and the journey takes 3h 35m. BlaBlaCar Bus also services this route every 4 hours.

Operators

Trip Overview

Bus