Bus Strasbourg to Main from €28 | Tickets & Timetables

Trip Overview

The average bus between Strasbourg and Main takes 4h 32m and the fastest bus takes 4h 14m. The bus service runs several times per day from Strasbourg to Main. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 32m
Duration: 241 km
Distance: €28
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from Strasbourg - L'Étoile Park Bus Station to Frankfurt - Airport Bus Stationbus BlaBlaCar Bus

4h 56m

€22–40

Strasbourg to Main bus times

Buses run every 4 hours between Strasbourg and Main. The earliest departure is at 3:30 AM at night, and the last departure from Strasbourg is at 8:35 PM which arrives into Main at 1:49 AM. All services require a transfer at Frankfurt - Airport Bus Station and take an average of 4h 32m. The schedules shown below are for the next available departures.

Departing Tuesday, September 1, 2026

8:50 AM → 1:09 PM
4h 19m • 1 change
9:00 AM → 1:39 PM
4h 39m • 1 change
10:25 AM → 2:39 PM
4h 14m • 1 change
1:50 PM → 6:24 PM
4h 34m • 1 change
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Departing Wednesday, September 2, 2026

3:30 AM → 9:54 AM
6h 24m • 1 change
8:50 AM → 1:09 PM
4h 19m • 1 change
9:00 AM → 1:39 PM
4h 39m • 1 change
10:25 AM → 2:39 PM
4h 14m • 1 change
Show more

Departing Thursday, September 3, 2026

3:30 AM → 9:54 AM
6h 24m • 1 change
8:50 AM → 1:09 PM
4h 19m • 1 change
9:00 AM → 1:39 PM
4h 39m • 1 change
10:25 AM → 2:39 PM
4h 14m • 1 change
Show more

Departing Friday, September 4, 2026

3:30 AM → 9:54 AM
6h 24m • 1 change
8:50 AM → 1:09 PM
4h 19m • 1 change
9:00 AM → 1:39 PM
4h 39m • 1 change
10:25 AM → 2:39 PM
4h 14m • 1 change
Show more

Departing Saturday, September 5, 2026

3:30 AM → 9:54 AM
6h 24m • 1 change
8:50 AM → 1:09 PM
4h 19m • 1 change
9:00 AM → 1:39 PM
4h 39m • 1 change
10:25 AM → 2:39 PM
4h 14m • 1 change
Show more

Departing Sunday, September 6, 2026

3:30 AM → 9:54 AM
6h 24m • 1 change
8:50 AM → 1:09 PM
4h 19m • 1 change
9:00 AM → 1:39 PM
4h 39m • 1 change
10:25 AM → 2:39 PM
4h 14m • 1 change
Show more

Departing Monday, September 7, 2026

3:30 AM → 9:54 AM
6h 24m • 1 change
8:50 AM → 1:09 PM
4h 19m • 1 change
9:00 AM → 1:39 PM
4h 39m • 1 change
10:25 AM → 2:39 PM
4h 14m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Strasbourg to Main? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.