The average bus between Strasbourg and Vesoul takes 6h 58m and the fastest bus takes 4h 15m. The bus service runs several times per day from Strasbourg to Vesoul. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Strasbourg and Vesoul. The earliest departure is at 5:40 AM in the morning, and the last departure from Strasbourg is at 9:15 PM which arrives into Vesoul at 7:21 AM. All services require a transfer, and take on average 6h 58m. The schedules shown below are for the next available departures.

5h 40m • 1 change

4h 15m • 1 change
Arrives next day

11h 15m • 1 change

5h 31m • 1 change

10h 1m • 1 change

4h 15m • 1 change
Arrives next day

10h 6m • 1 change
Want to know about travelling from Strasbourg to Vesoul? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Strasbourg to Vesoul. However, there are services departing from Strasbourg station and arriving at Vesoul station via Besançon. The journey, including transfers, takes approximately 6h 58m.
Strasbourg to Vesoul bus services, operated by FlixBus, depart from Strasbourg station.
Strasbourg to Vesoul bus services, operated by FlixBus, arrive at Pôle Multimodal station.
The distance between Strasbourg and Vesoul is 159.7 km. The road distance is 314 km.
You can take a bus from Strasbourg to Pôle Multimodal via PEM Viotte in around 5h 56m.