The average bus between Syracuse and Siena takes 16h 21m and the fastest bus takes 15h 9m. The bus service runs several times per day from Syracuse to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Syracuse and Siena. The earliest departure is at 7:06 AM in the morning, and the last departure from Syracuse is at 4:36 PM which arrives into Siena at 7:45 AM. All services require a transfer, and take on average 16h 21m. The schedules shown below are for the next available departures.
Arrives next day

17h 34m • 1 change
Arrives next day

15h 9m • 1 change
Arrives next day

17h 34m • 1 change
Arrives next day

15h 9m • 1 change
Arrives next day

17h 34m • 1 change
Arrives next day

15h 9m • 1 change
Arrives next day

17h 34m • 1 change
Arrives next day

15h 9m • 1 change
Arrives next day

17h 34m • 1 change
Arrives next day

15h 9m • 1 change
Want to know about travelling from Syracuse to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Syracuse to Siena. However, there are services departing from Syracuse station and arriving at Siena station via Catania Airport. The journey, including transfers, takes approximately 16h 21m.
Syracuse to Siena bus services, operated by Interbus, depart from Siracusa - Von Platen station.
Syracuse to Siena bus services, operated by Interbus, arrive at Siena station.
Book your Syracuse to Siena bus tickets online with Interbus and FlixBus.
The distance between Syracuse and Siena is 771 km. The road distance is 1,066 km.
You can take a bus from Siracusa - Von Platen to Siena via Catania Airport in around 15h 54m.