The average bus between Syracuse and Lake Erie takes 3h 50m and the fastest bus takes 3h 25m. The bus service runs several times per day from Syracuse to Lake Erie. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Syracuse and Lake Erie. The earliest departure is at 12:55 AM at night, and the last departure from Syracuse is at 7:35 PM which arrives into Lake Erie at 11:29 PM. All services require a transfer at Buffalo and take an average of 3h 50m. The schedules shown below are for the next available departures.

3h 25m • 1 change

3h 36m • 1 change

3h 46m • 1 change

3h 44m • 1 change

4h 17m • 1 change

4h 12m • 1 change

3h 39m • 1 change

3h 25m • 1 change

4h 17m • 1 change

4h 12m • 1 change

3h 39m • 1 change

3h 25m • 1 change

4h 17m • 1 change

4h 12m • 1 change

3h 39m • 1 change

3h 25m • 1 change
Want to know about travelling from Syracuse to Lake Erie? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Syracuse to Lake Erie. However, there are services departing from Syracuse station and arriving at Lake Erie station via Buffalo. The journey, including transfers, takes approximately 3h 50m.
Syracuse to Lake Erie bus services, operated by Flixbus USA, depart from Syracuse station.
Syracuse to Lake Erie bus services, operated by Flixbus USA, arrive at Buffalo station.
The distance between Syracuse and Lake Erie is 439.1 km. The road distance is 264 km.
Trailways operates a bus from Syracuse to Buffalo every 4 hours. Tickets cost $28–100 and the journey takes 3h 10m. Two other operators also service this route.