The average bus between Syracuse and Mississippi takes 38h 10m and the fastest bus takes 34h 5m. The bus service runs several times per day from Syracuse to Mississippi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Syracuse and Mississippi. The earliest departure is at 3:15 AM at night, and the last departure from Syracuse is at 2:00 PM which arrives into Mississippi at 7:15 AM. All services require a transfer at New York Midtown and take an average of 38h 10m. The schedules shown below are for the next available departures.
Arrives next day


33h 5m • 2 changes
Arrives +2 days


41h 15m • 2 changes
Arrives next day


33h 5m • 2 changes
Arrives +2 days


41h 15m • 2 changes
Arrives next day


33h 5m • 2 changes
Arrives +2 days


41h 15m • 2 changes
Arrives next day


33h 5m • 2 changes
Arrives +2 days


41h 15m • 2 changes
Want to know about travelling from Syracuse to Mississippi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Syracuse to Mississippi. However, there are services departing from Syracuse station and arriving at Mississippi station via New York Midtown. The journey, including transfers, takes approximately 38h 10m.
Syracuse to Mississippi bus services, operated by Flixbus USA, depart from Syracuse Bus Station.
Syracuse to Mississippi bus services, operated by Flixbus USA, arrive at Jackson station.
Book your Syracuse to Mississippi bus tickets online with Flixbus USA and Greyhound USA.
The distance between Syracuse and Mississippi is 1,630.8 km. The road distance is 2,627 km.
You can take a bus from Syracuse Bus Station to Jackson via New York Midtown and Atlanta Bus Station in around 32h 50m.