The average bus between Syracuse and St. Louis takes 41h 36m and the fastest bus takes 41h 15m. There is at least one bus per day from Syracuse to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Syracuse and St. Louis. The earliest departure is at 7:00 AM in the morning, and the last departure from Syracuse is at 7:00 AM which arrives into St. Louis at 11:15 PM. All services require a transfer at Buffalo and take an average of 41h 36m. The schedules shown below are for the next available departures.
Want to know about travelling from Syracuse to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Syracuse to St. Louis. However, there are services departing from Syracuse station and arriving at St. Louis station via Buffalo. The journey, including transfers, takes approximately 41h 36m.
Syracuse to St. Louis bus services, operated by Greyhound USA, depart from Syracuse Bus Station.
Syracuse to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Book your Syracuse to St. Louis bus tickets online with Greyhound USA and Barons Bus.
The distance between Syracuse and St. Louis is 1,278.1 km. The road distance is 1,624 km.
You can take a bus from Syracuse Bus Station to St Louis Bus Station via Buffalo, Buffalo, NY, Youngstown, OH, Youngstown Bus Stop, and Pittsburgh Intermodal Station in around 23h 10m.
