The average bus between Syracuse and West Seneca takes 3h 56m and the fastest bus takes 3h 25m. The bus service runs several times per day from Syracuse to West Seneca. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Syracuse and West Seneca. The earliest departure is at 1:30 AM at night, and the last departure from Syracuse is at 7:35 PM which arrives into West Seneca at 11:37 PM. All services require a transfer at Buffalo and take an average of 3h 56m. The schedules shown below are for the next available departures.

3h 25m • 1 change

4h 22m • 1 change

4h 28m • 1 change

4h 3m • 1 change

4h 6m • 1 change

3h 31m • 1 change

3h 43m • 1 change

3h 45m • 1 change

4h 6m • 1 change

3h 31m • 1 change

3h 43m • 1 change

3h 45m • 1 change

4h 6m • 1 change

3h 31m • 1 change

3h 43m • 1 change

3h 45m • 1 change

4h 6m • 1 change

3h 31m • 1 change

3h 43m • 1 change

3h 45m • 1 change
Want to know about travelling from Syracuse to West Seneca? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Syracuse to West Seneca. However, there are services departing from Syracuse station and arriving at West Seneca station via Buffalo. The journey, including transfers, takes approximately 3h 56m.
Syracuse to West Seneca bus services, operated by Greyhound USA, depart from Syracuse Bus Station.
Syracuse to West Seneca bus services, operated by Greyhound USA, arrive at Buffalo station.
The distance between Syracuse and West Seneca is 217 km. The road distance is 266 km.
Flixbus USA operates a bus from Syracuse Bus Station to Buffalo every 2 hours. Tickets cost $24–45 and the journey takes 3h 5m. Two other operators also service this route.