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Syracuse, Ny to Manhattan buses

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Trip Overview

The average bus between Syracuse, Ny and Manhattan takes 5h 2m and the fastest bus takes 4h 30m. There is a bus service every few hours from Syracuse, Ny to Manhattan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 2m
Duration
261 mi
Distance
$150
Average price
Every 2 hours
Frequency

Syracuse, Ny to Manhattan bus times

Buses run every 2 hours between Syracuse, Ny and Manhattan. The earliest departure is at 12:20 AM at night, and the last departure from Syracuse, Ny is at 9:00 PM which arrives into Manhattan at 2:05 AM. All services run direct with no transfers required, and take on average 5h 2m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    bus bus 5h 20m • Direct
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    bus bus 5h 5m • Direct
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    bus bus 5h 15m • Direct
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    bus bus 4h 45m • Direct
  • Show more

Departing Monday, November 9, 2026

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    bus bus 4h 30m • Direct
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    bus bus 5h 20m • Direct
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    bus bus 5h 5m • Direct
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    bus bus 5h 15m • Direct
  • Show more

Departing Tuesday, November 10, 2026

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    bus bus 4h 30m • Direct
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    bus bus 5h 20m • Direct
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    bus bus 5h 5m • Direct
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    bus bus 5h 15m • Direct
  • Show more

Departing Wednesday, November 11, 2026

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    bus bus 4h 30m • Direct
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    bus bus 5h 20m • Direct
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    bus bus 5h 15m • Direct
  •  → 

    bus bus 4h 45m • Direct
  • Show more

Departing Thursday, November 12, 2026

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    bus bus 4h 30m • Direct
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    bus bus 5h 20m • Direct
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    bus bus 5h 5m • Direct
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    bus bus 5h 15m • Direct
  • Show more

Departing Friday, November 13, 2026

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    bus bus 4h 30m • Direct
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    bus bus 5h 20m • Direct
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    bus bus 5h 5m • Direct
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    bus bus 5h 15m • Direct
  • Show more

Departing Saturday, November 14, 2026

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    bus bus 4h 30m • Direct
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    bus bus 5h 20m • Direct
  •  → 

    bus bus 5h 5m • Direct
  •  → 

    bus bus 5h 15m • Direct
  • Show more

Frequently asked questions

Want to know about travelling from Syracuse, Ny to Manhattan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Syracuse, Ny to Manhattan.ExpandLaunch map view
  • Distance: 260.6 mi
  • Duration: 5h 2m

What companies run services between Syracuse, Ny, NY, USA and Manhattan, NY, USA?

Greyhound USA operates a bus from Syracuse Bus Station to Port Authority Bus Terminal every 2 hours. Tickets cost $45–75 and the journey takes 4h 45m. Two other operators also service this route.

Operators