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Syracuse, Ny to St. Louis buses

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Trip Overview

The bus between Syracuse, Ny and St. Louis takes 26h 50m. There is at least one bus per day from Syracuse, Ny to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

26h 50m
Duration
1,232 mi
Distance
$273
Average price
Once daily
Frequency

Syracuse, Ny to St. Louis bus times

Buses run once daily between Syracuse, Ny and St. Louis. The service departs Syracuse, Ny at 9:00 PM at night, which arrives into St. Louis at 22:50:00. All services require a transfer, and take on average 26h 50m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

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    Arrives next day

    Greyhound USAGreyhound USA26h 50m • 1 change

Departing Thursday, November 5, 2026

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    Arrives next day

    Greyhound USAGreyhound USA26h 50m • 1 change

Departing Friday, November 6, 2026

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    Arrives next day

    Greyhound USAGreyhound USA26h 50m • 1 change

Departing Saturday, November 7, 2026

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    Arrives next day

    Greyhound USAGreyhound USA26h 50m • 1 change

Departing Sunday, November 8, 2026

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    Arrives next day

    Greyhound USAGreyhound USA26h 50m • 1 change

Departing Monday, November 9, 2026

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    Arrives next day

    Greyhound USAGreyhound USA26h 50m • 1 change

Frequently asked questions

Want to know about travelling from Syracuse, Ny to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Syracuse, Ny to St. Louis.ExpandLaunch map view
  • Distance: 1,232.1 mi
  • Duration: 26h 50m

What companies run services between Syracuse, Ny, NY, USA and St. Louis, MO, USA?

You can take a bus from Syracuse Bus Station to St Louis Bus Station via Newark Penn Station in around 27h 20m.

Operators