The average bus between Tallahassee and Key West takes 21h and the fastest bus takes 18h 37m. The bus service runs several times per day from Tallahassee to Key West. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Tallahassee and Key West. The earliest departure is at 11:50 AM in the morning, and the last departure from Tallahassee is at 9:05 PM which arrives into Key West at 3:42 PM. All services require a transfer at Miami Airport Station and take an average of 21h. The schedules shown below are for the next available departures.
Arrives next day


25h 12m • 2 changes
Arrives next day


18h 37m • 2 changes
Arrives next day


25h 12m • 2 changes
Arrives next day


18h 37m • 2 changes
Want to know about travelling from Tallahassee to Key West? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Tallahassee to Key West. However, there are services departing from Tallahassee station and arriving at Key West station via Miami Airport Station station. The journey, including transfers, takes approximately 21h.
Tallahassee to Key West bus services, operated by Flixbus USA, depart from Tallahassee station.
Tallahassee to Key West bus services, operated by Flixbus USA, arrive at N Roosevelt & 3rd Street station.
Book your Tallahassee to Key West bus tickets online with Flixbus USA, Greyhound USA and Key West Transit.
The distance between Tallahassee and Key West is 699 km. The road distance is 1,160 km.
You can take a bus from Tallahassee to N Roosevelt & 3rd Street via Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 19h 56m.