The average bus between Tampa Airport (TPA) and Key Largo takes 14h 36m and the fastest bus takes 11h 27m. The bus service runs several times per day from Tampa Airport (TPA) to Key Largo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Tampa Airport (TPA) and Key Largo. The earliest departure is at 12:53 PM in the afternoon, and the last departure from Tampa Airport (TPA) is at 9:52 PM which arrives into Key Largo at 9:20 AM. All services require a transfer at Marion Transit Center and take an average of 14h 36m. The schedules shown below are for the next available departures.
Arrives next day


17h 31m • 2 changes
Arrives next day


14h 30m • 2 changes
Arrives next day


16h 31m • 2 changes
Arrives next day


11h 30m • 2 changes
Arrives next day


16h 31m • 2 changes
Arrives next day


11h 30m • 2 changes
Want to know about travelling from Tampa Airport (TPA) to Key Largo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Tampa Airport (TPA) to Key Largo. However, there are services departing from Tampa Airport (TPA) station and arriving at Key Largo station via Miami Airport Station station. The journey, including transfers, takes approximately 14h 36m.
Tampa Airport (TPA) to Key Largo bus services, operated by Hillsborough Area Regional Transit, depart from Tampa Bus Station.
Tampa Airport (TPA) to Key Largo bus services, operated by Hillsborough Area Regional Transit, arrive at Key Largo Bus Stop station.
The distance between Tampa Airport (TPA) and Key Largo is 382.5 km. The road distance is 577 km.
You can take a bus from TPA Internat'l Airport Post Office to Key Largo Bus Stop via Marion Transit Center, Tampa Bus Station, and Miami Airport Station in around 10h 16m.