The average bus between Tampa and Florida Keys takes 16h 6m and the fastest bus takes 13h 40m. There is at least one bus per day from Tampa to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Tampa and Florida Keys. The earliest departure is at 1:45 PM in the afternoon, and the last departure from Tampa is at 10:35 PM which arrives into Florida Keys at 12:15 PM. All services require a transfer at Miami Airport Station and take an average of 16h 6m. The schedules shown below are for the next available departures.
Want to know about travelling from Tampa to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Tampa to Florida Keys. However, there are services departing from Tampa station and arriving at Florida Keys station via Miami Airport Station station. The journey, including transfers, takes approximately 16h 6m.
Tampa to Florida Keys bus services, operated by Flixbus USA, depart from Tampa Bus Station.
Tampa to Florida Keys bus services, operated by Flixbus USA, arrive at Big Pine Key station.
The distance between Tampa and Florida Keys is 377.8 km. The road distance is 691 km.
You can take a bus from Tampa Bus Station to Florida Keys via Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 12h 10m.