The average bus between Tampa and Key West (Island) takes 16h 44m and the fastest bus takes 13h 55m. The bus service runs several times per day from Tampa to Key West (Island). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Tampa and Key West (Island). The earliest departure is at 1:45 PM in the afternoon, and the last departure from Tampa is at 10:35 PM which arrives into Key West (Island) at 12:30 PM. All services require a transfer, and take on average 16h 44m. The schedules shown below are for the next available departures.
Arrives next day

19h 45m • 1 change
Arrives next day

16h 55m • 1 change
Arrives next day

18h 15m • 1 change
Arrives next day

13h 55m • 1 change
Arrives next day

18h 15m • 1 change
Arrives next day

13h 55m • 1 change
Arrives next day

18h 15m • 1 change
Arrives next day

13h 55m • 1 change
Want to know about travelling from Tampa to Key West (Island)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Tampa to Key West (Island). However, there are services departing from Tampa station and arriving at Key West (Island) station via Miami Airport Station station. The journey, including transfers, takes approximately 16h 44m.
Tampa to Key West (Island) bus services, operated by Flixbus USA, depart from Tampa Bus Station.
Tampa to Key West (Island) bus services, operated by Flixbus USA, arrive at Key West Airport station.
Book your Tampa to Key West (Island) bus tickets online with Flixbus USA and Greyhound USA.
The distance between Tampa and Key West (Island) is 383.1 km. The road distance is 719 km.
You can take a bus from Tampa Bus Station to Key West Airport via Miami Airport Station in around 11h 50m.