The average bus between Thame and Isleworth takes 3h 40m and the fastest bus takes 2h 47m. The bus service runs several times per day from Thame to Isleworth. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Thame and Isleworth. The earliest departure is at 7:15 AM in the morning, and the last departure from Thame is at 8:10 PM which arrives into Isleworth at 6:51 AM. All services require a transfer at High Wycombe BusStn and take an average of 3h 40m. The schedules shown below are for the next available departures.


3h 12m • 2 changes

2h 57m • 2 changes

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2h 57m • 2 changes

2h 59m • 2 changes

3h 3m • 2 changes

3h 3m • 2 changes

3h 12m • 2 changes

2h 57m • 2 changes

2h 57m • 2 changes

2h 57m • 2 changes

3h 12m • 2 changes

2h 57m • 2 changes

2h 57m • 2 changes

2h 57m • 2 changesWant to know about travelling from Thame to Isleworth? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Thame to Isleworth. However, there are services departing from Thame station and arriving at Isleworth station via High Wycombe BusStn. The journey, including transfers, takes approximately 3h 40m.
Thame to Isleworth bus services, operated by Red Rose Travel, depart from Town Hall station.
Thame to Isleworth bus services, operated by Red Rose Travel, arrive at Hounslow Bus Station.
The distance between Thame and Isleworth is 53.4 km. The road distance is 71 km.
You can take a bus from Town Hall to Hounslow Bus Station via High Wycombe BusStn, Belmont Road, and Uxbridge Station in around 2h 51m.