The average bus between Thame and Southampton takes 3h 55m and the fastest bus takes 3h 25m. The bus service runs several times per day from Thame to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Thame and Southampton. The earliest departure is at 1:15 AM at night, and the last departure from Thame is at 7:45 PM which arrives into Southampton at 12:05 AM. All services require a transfer at Thornhill Park and Ride and take an average of 3h 55m. The schedules shown below are for the next available departures.


3h 45m • 2 changes

4h 5m • 2 changes

3h 35m • 2 changes

3h 50m • 2 changes

3h 39m • 2 changes

3h 30m • 2 changes

3h 55m • 2 changes

3h 25m • 2 changes

3h 39m • 2 changes

3h 30m • 2 changes

3h 55m • 2 changes

4h 10m • 2 changes

4h 19m • 2 changes

3h 25m • 2 changes

3h 55m • 2 changes

3h 55m • 2 changes

8h 35m • 2 changes

3h 25m • 2 changes

3h 55m • 2 changes

3h 55m • 2 changesWant to know about travelling from Thame to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Thame to Southampton. However, there are services departing from Thame station and arriving at Southampton station via Heathrow Terminal 5. The journey, including transfers, takes approximately 3h 55m.
Thame to Southampton bus services, operated by Oxford Bus Company, depart from Thornhill Park and Ride station.
Thame to Southampton bus services, operated by Oxford Bus Company, arrive at Coach Station.
The distance between Thame and Southampton is 98.4 km. The road distance is 185 km.
You can take a bus from Town Hall to Coach Station via Thornhill Park and Ride and Heathrow Terminal 5 in around 3h 41m.