The average bus between Thousand Oaks and Santa Ana takes 4h 33m and the fastest bus takes 3h 43m. The bus service runs several times per day from Thousand Oaks to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Thousand Oaks and Santa Ana. The earliest departure is at 5:05 AM in the morning, and the last departure from Thousand Oaks is at 6:17 PM which arrives into Santa Ana at 10:24 PM. All services require a transfer at Figueroa St & Pico Blvd and take an average of 4h 33m. The schedules shown below are for the next available departures.


3h 43m • 2 changes


4h 2m • 2 changes


4h 15m • 2 changes


4h 35m • 2 changes


3h 43m • 2 changes


4h 2m • 2 changes


4h 15m • 2 changes


4h 35m • 2 changes


3h 43m • 2 changes


4h 2m • 2 changes


4h 15m • 2 changes


4h 35m • 2 changes


3h 43m • 2 changes


4h 2m • 2 changes


4h 15m • 2 changes


4h 35m • 2 changes
Want to know about travelling from Thousand Oaks to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Thousand Oaks to Santa Ana. However, there are services departing from Thousand Oaks station and arriving at Santa Ana station via Figueroa St & Pico Blvd. The journey, including transfers, takes approximately 4h 33m.
Thousand Oaks to Santa Ana bus services, operated by LA DOT, depart from Hampshire Rd & Townsgate Rd station.
Thousand Oaks to Santa Ana bus services, operated by LA DOT, arrive at Disneyland Employee's Entrance station.
The distance between Thousand Oaks and Santa Ana is 101.2 km. The road distance is 149 km.
You can take a bus from Hampshire Rd & Townsgate Rd to Main-Civic Center via Figueroa St & Pico Blvd, Flower / Pico, Disneyland Employee's Entrance, and Harbor-East Shuttle Area in around 4h 41m.