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Times Square to Middletown (Station) buses

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Trip Overview

The average bus between Times Square and Middletown (Station) takes 6h 28m and the fastest bus takes 5h 31m. The bus service runs several times per day from Times Square to Middletown (Station). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 28m
Duration
225 mi
Distance
$48
Average price
Twice daily
Frequency

Times Square to Middletown (Station) bus times

Buses run twice daily between Times Square and Middletown (Station). The earliest departure is at 9:55 AM in the morning, and the last departure from Times Square is at 10:50 PM which arrives into Middletown (Station) at 5:42 AM. All services require a transfer at Harrisburg Bus Station and take an average of 6h 28m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Greyhound USARabbit Transit6h 52m • 1 change

Departing Wednesday, November 11, 2026

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    Greyhound USARabbit Transit5h 38m • 1 change
  •  → 

    Greyhound USARabbit Transit6h 49m • 1 change
  •  → 

    Arrives next day

    Greyhound USARabbit Transit6h 52m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Greyhound USARabbit Transit5h 38m • 1 change
  •  → 

    Greyhound USARabbit Transit6h 49m • 1 change
  •  → 

    Arrives next day

    Greyhound USARabbit Transit6h 52m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Greyhound USARabbit Transit5h 38m • 1 change
  •  → 

    Greyhound USARabbit Transit6h 49m • 1 change
  •  → 

    Arrives next day

    Greyhound USARabbit Transit8h 36m • 1 change

Departing Saturday, November 14, 2026

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    Greyhound USARabbit Transit5h 31m • 1 change
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    Greyhound USARabbit Transit6h 26m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Greyhound USARabbit Transit6h 52m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Greyhound USARabbit Transit5h 38m • 1 change

Frequently asked questions

Want to know about travelling from Times Square to Middletown (Station)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Times Square to Middletown (Station).ExpandLaunch map view
  • Distance: 225.5 mi
  • Duration: 6h 28m

What companies run services between Times Square, NY, USA and Middletown (Station), PA, USA?

Greyhound USA operates a bus from Port Authority Bus Terminal to Harrisburg Bus Station 5 times a day. Tickets cost $35–60 and the journey takes 3h 35m.

Operators