The average bus between Tlaxcala and Cancún takes 26h 57m and the fastest bus takes 26h 45m. The bus service runs several times per day from Tlaxcala to Cancún. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Tlaxcala and Cancún. The earliest departure is at 11:00 AM in the morning, and the last departure from Tlaxcala is at 12:30 PM which arrives into Cancún at 4:15 PM. All services require a transfer at Puebla CAPU and take an average of 26h 57m. The schedules shown below are for the next available departures.
Arrives next day

28h 10m • 1 change
Arrives next day

27h 45m • 1 change
Arrives next day

28h 10m • 1 change
Arrives next day

27h 45m • 1 change
Arrives next day

28h 10m • 1 change
Arrives next day

27h 45m • 1 change
Arrives next day

28h 10m • 1 change
Arrives next day

27h 45m • 1 change
Arrives next day

28h 10m • 1 change
Arrives next day

27h 45m • 1 change
Want to know about travelling from Tlaxcala to Cancún? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Tlaxcala to Cancún. However, there are services departing from Tlaxcala station and arriving at Cancún station via Terminal de Autobuses ADO Cancún. The journey, including transfers, takes approximately 26h 57m.
Tlaxcala to Cancún bus services, operated by Autobuses Valles, depart from Puebla Capu station.
Tlaxcala to Cancún bus services, operated by Autobuses Valles, arrive at Terminal de Autobuses ADO Cancún station.
The distance between Tlaxcala and Cancún is 1,202 km. The road distance is 1,618 km.
ADO operates a bus from Puebla Capu to Terminal de Autobuses ADO Cancún twice daily. Tickets cost $2,100–4,400 and the journey takes 26h.