The average bus between Tlaxcala and Guadalajara takes 9h 43m and the fastest bus takes 9h. There is a bus service every few hours from Tlaxcala to Guadalajara. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Tlaxcala and Guadalajara. The earliest departure is at 5:00 AM in the morning, and the last departure from Tlaxcala is at 9:00 PM which arrives into Guadalajara at 6:30 AM. All services require a transfer at México TAPO and take an average of 9h 43m. The schedules shown below are for the next available departures.



9h 20m • 3 changes



9h 50m • 3 changes



9h 50m • 3 changes



9h 40m • 3 changes



10h • 3 changes



9h 50m • 3 changes



9h 50m • 3 changes



9h 30m • 3 changes



10h • 3 changes



9h 50m • 3 changes



9h 50m • 3 changes



9h 30m • 3 changes



10h • 3 changes



9h 50m • 3 changes



9h 50m • 3 changes



9h 30m • 3 changes
Want to know about travelling from Tlaxcala to Guadalajara? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Tlaxcala to Guadalajara. However, there are services departing from Tlaxcala station and arriving at Guadalajara station via México TAPO. The journey, including transfers, takes approximately 9h 43m.
Tlaxcala to Guadalajara bus services, operated by Autobuses Supra, depart from Tlaxcala station.
Tlaxcala to Guadalajara bus services, operated by Autobuses Supra, arrive at Nueva Central Camionera de Guadalajara Mod 1 station.
The distance between Tlaxcala and Guadalajara is 562.8 km. The road distance is 650 km.
You can take a bus from Tlaxcala to Nueva Central Camionera de Guadalajara Mod 1 via México TAPO, San Lázaro Oriente, Teatro Blanquita, Mina, Central del Norte, and Terminal Central de Autobuses del Norte in around 9h 21m.